Any quantum system in this universe tends to move to its lowest energy configuration. Which is what decides its structure and properties. Hence calculating the lowest Eigen Value (aka Lowest Energy) of a Quantum System is a fundamental problem in physics, chemistry, materials etc.
We can do this at production scale "today" since 1990's.
Quantum Many-Body Physics
Superconductivity
Super Alloys
Catalysis
Protein Folding
Condensed Matter Physics
Battery Design
Solar Capture
...
Quantum Chemistry
Quantum Materials
...
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